Combination of Loop Diuretics and Thiazide Diuretics for Decompensated Heart Failure: The CLOROTIC Trial

Combination of Loop Diuretics and Thiazide Diuretics for Decompensated Heart Failure: The CLOROTIC Trial

From the CLOROTIC trial, the addition of hydrochlorothiazide (HCTZ) to loop diuretics improved diuretic response in patients with acute heart failure. Dr. Joan Carles Trullas and colleagues of Hospital d'Olot i comarcal de la Garrotxa, Spain, reported in the February 1 issue of the European Heart Journal.

In the CLOROTIC study, 230 patients (48% female, 83 years old) with acute heart failure were randomi...
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