Switching from Warfarin to DOAC in Frail Elderly Patients with Atrial Fibrillation: the FRAIL-AF Trial

Switching from Warfarin to DOAC in Frail Elderly Patients with Atrial Fibrillation: the FRAIL-AF Trial

According to the FRAIL-AF trial, frail older patients who switched from warfarin to direct oral anticoagulants (DOACs) for atrial fibrillation (AF) had a 69% increased risk of bleeding compared with those who continued on warfarin. Dr. Linda P.T. Joosten, Utrecht University, The Netherlands, presented at the Hot Line session of ESC Congress 2023.

The FRAIL-AF trial enrolled non-valvular AF patients receiving warfarin treatment from January 2018...
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