Cutting Balloon versus Standard Balloon for Lesion Preparation of Drug-Coated Balloon Treatment in De-novo Coronary Artery Lesions: The NATURE Trial

Cutting Balloon versus Standard Balloon for Lesion Preparation of Drug-Coated Balloon Treatment in De-novo Coronary Artery Lesions: The NATURE Trial

The NATURE trial, a multicenter study conducted in Japan, suggested that cutting balloons may be superior to standard balloons in achieving adequate lesion preparation and reducing bailout stenting during drug-coated balloon (DCB) treatment for de novo coronary lesions, according to a study presented by Dr. Ken Kozuma, Teikyo University, Japan, in the Scientific Abstracts session at TCT 2025.

In the NATURE trial, 210 patients with a single de novo coronary lesion (reference diameter 2.5&ndas...
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